survival rate – Communicable Diseases Research

Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Article

Published on 2023-01-302022-11-16
Journal: Journal of ethnopharmacology
[Category] 신종인플루엔자, 치료기술,

Can torque teno virus be a predictor of SARS-CoV-2 disease progression in cancer patients?

Article

Published on 2022-12-012022-11-15
Journal: Journal of infection and chemotherapy : official j
[Category] COVID19(2023년), SARS, 치료기술,

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice

Article

Published on 2022-11-012022-11-15
Journal: Inflammation research : official journal of the Eu
[Category] 유전자 메커니즘, 진단,

[키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome alleviate Analysis Anti-inflammatory anti-inflammatory property anti-inflammatory response ARDS CFZ Clofazimine coronavirus disease COVID-19 Critical decrease disease Diseases distress down-regulate histological change hyperimmune response IL-1β immune IMPROVE increasingly Infectious disease Inflammatory information inhibit involved lipopolysaccharide LPS lung Lung injury Macrophage macrophages mechanism mice Molecular biology pathway pharmacological mechanism potential molecular profile proliferation protective effect Protein protein expression Proteomic analysis proteomics proteomics. Pulmonary edema Quantitative Signal transduction Signaling significantly survival rate syndrome therapeutic strategy TNF-α
[DOI] 10.1007/s00011-022-01623-w PMC 바로가기

The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals

Article

Published on 2022-09-132022-11-15
Journal: Frontiers in Immunology
[Category] SARS, 변종, 치료제,

[키워드] analyzed anti-SARS-CoV-2 anticancer Bone marrow Cancer cancer cell cancer cell lines cancer patient Cancer patients chemokine combating cordycepin cordycepin (CD). correlated COVID-19 COVID-19 pandemic domain exhibited expression functional healthy healthy individual highest immune Immune cell infiltration immune infiltration individuals information inhibit Invasion ISG20 ISG20 expression isoform less Lymphocytes lymphoid tissues marker Methylation MHC molecule mRNA expression mutant N6 N6-dimethyladenosine (m 6 2A) outcome overexpression promoter receptors Regulation SARS-CoV-2 SARS-COV-2 infection significantly significantly increased significantly lower small molecule survival survival rate susceptibility the median therapeutic potential tissue tissues traditional Chinese medicines treat tumorigenesis underlie virus were used
[DOI] 10.3389/fimmu.2022.958898 PMC 바로가기

Network Pharmacology and Bioinformatics Analysis Identifies Potential Therapeutic Targets of Paxlovid Against LUAD/COVID-19

Article

Published on 2022-09-082022-11-16
Journal: Frontiers in Endocrinology
[Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome Against Analysis approved bioinformatics bioinformatics. caused Clinical characteristics Clinical data contagious coronavirus Coronavirus disease 2019 correlation country COVID-19 COX Cytoscape downloaded drug drug target DrugBank evaluate evaluated Fatality rate FDA Features food functional Gene Expression GeneCards Genes GO enrichment analysis IL-17 IL12B IL6 include infected with COVID-19 Interaction KEGG LBP lung adenocarcinoma (LUAD) lung cancer patient management mechanism modulate molecular molecular docking Mortality NCBI network network pharmacology pandemic pathway Pathway analysis Patient Paxlovid Pharmacology Potential potential therapeutic target Prognosis prognostic receptor Regression model risk SARS-CoV-2 screened signaling pathway survival rate susceptibility SwissTargetPrediction target target gene TargetNet therapeutic target Transcriptome Treatment Venn diagram virus was performed was used while
[DOI] 10.3389/fendo.2022.935906 PMC 바로가기

Soluble urokinase Plasminogen Activator Receptor (suPAR) levels are predictive of COVID-19 severity: an Italian experience

Research article

Published on 2022-09-012022-10-05
Journal: Clinical immunology (Orlando, Fla.)
[Category] 바이오마커, 진단,

Effects of lymphocyte and neutrophil counts and their time courses on mortality in patients with postoperative pneumonia

Research

Published on 2022-08-262022-10-05
Journal: Scientific Reports
[Category] 바이오마커,

Assessment of Tocilizumab (Humanized Monoclonal Antibody) for Therapeutic Efficacy and Clinical Safety in Patients with Coronavirus Disease (COVID-19)

코로나바이러스 감염증(COVID-19) 환자의 치료 효능 및 임상 안전성에 대한 토실리주맙(인간화 단클론항체) 평가

Article

Published on 2022-08-102022-09-12
Journal: Medicina
[Category] SARS, 진단,

[키워드] activated acute respiratory distress added adverse effect airways alanine aminotransferase alkaline phosphatase ALP ALT analysis Anticoagulant ARDS assessment Autoimmune Bacterial baseline C-reactive protein characterized clinical coagulation parameter Coagulopathy control group COVID-19 COVID-19 cases COVID-19 patient COVID-19 patients CRP CRS Cytokine release syndrome Cytokine storm D-dimer discharged Efficacy Endpoint expired fatality ferritin Follow-up humanized monoclonal antibody include infection rate Inflammatory inflammatory conditions inflammatory parameter inflammatory parameters INR institution institutional protocol International lactate dehydrogenase LDH Manifestations material normalized patients of COVID-19 Platelet Pneumonia presenting Prothrombin time provided Pulmonary edema raised receiving respiratory tract infection Result Safety severe COVID-19 patients severe disease significantly higher statistically significant difference survival rate syndrome Teaching the disease the patient therapeutic efficacy Tocilizumab tocilizumab. treat Treatment Treatment protocol treatment regimen was performed
[DOI] 10.3390/medicina58081076 PMC 바로가기 [Article Type] Article

The Efficacy of Aprotinin Combinations with Selected Antiviral Drugs in Mouse Models of Influenza Pneumonia and Coronavirus Infection Caused by SARS-CoV-2

SARS-CoV-2로 인한 인플루엔자 폐렴 및 코로나바이러스 감염의 마우스 모델에서 선택된 항바이러스제와 아프로티닌 조합의 효능

Article

Published on 2022-08-052022-09-11
Journal: Molecules
[Category] SARS, 치료제,

Clinical Effect of Early administration of Tocilizumab Following the Initiation of Corticosteroid Therapy for Patients with COVID-19

Article

Published on 2022-08-012022-10-05
Journal: Journal of infection and chemotherapy : official j
[Category] COVID19(2023년), SARS, 임상, 진단, 치료기술,

[키워드] acute respiratory syndrome addition administration analyzed baseline blood cell count C-reactive protein caused clinical Clinical characteristics combination therapy coronavirus Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 determine drug early administration Effect effective Efficacy evaluated global pandemic groups hospital Hospitalized Initiation maximum body temperature not significantly different oxygen-free day Patient patients with COVID-19 Result SARS-CoV-2 significant decrease significantly higher significantly lower significantly more survival rate Tocilizumab tocilizumab administration treated treating COVID-19 two groups white with COVID-19 Wuhan
[DOI] 10.1016/j.jiac.2022.08.021 [Article Type] Article